I.F. Akyildiz

PANACEA: A Cyber-Physical System for Early Detection and Mitigation of Infections


I.F. Akyildiz, Georgia Institute of Technology



In this talk, the design and implementation of a new cyber-physical system (CPS) named PANACEA (a solution or remedy for all difficulties or diseases in Latin), is presented as a closed-loop solution to the problem of early detection and mitigation of infections. PANACEA leverages cutting-edge technologies in the cyber (i.e., machine learning, big data analytics, cloud computing, security) and physical (i.e., bio-nanosensors, magnetic and wireless communications) domains to provide unprecedented sensing, monitoring, and drug-delivery capabilities to address ongoing bacterial infections. On the physical side, PANACEA will sense biological phenomena from nano (i.e., molecules, genes) to macroscale (i.e., body, organ, tissues). This is achieved through implantable bio-electronic devices engineered to detect the communication within human body cells, enabling the rise of a novel Internet of Bio-NanoThings paradigm. The physical side of PANACEA primarily addresses the design and implementation of a sub-mm-sized implantable, named RIMOR (explorer in Latin), a miniaturized electronic device able to detect the increase in the concentration of the quorum sensing signals generated by the bacteria and communicate the onset of the infection to a wearable hub. The cyber side of PANACEA will be tasked to (i) provide novel computational tools and infrastructures (i.e., deep learning, data compression and fusion algorithms) needed to analyze and interpret the sheer volume of data generated by the physical portion of the CPS; (ii) securely store and share patient’s past and current information with the PANACEA stakeholders (i.e., medical professionals, and other authorized users); and (iii) provide control feedback to the physical portion of PANACEA to swiftly address ongoing infections.



I. F. AKYILDIZ is the Ken Byers Chair Professor with the School of Electrical and Computer Engineering, Georgia Institute of Technology, Director of the Broadband Wireless Networking Laboratory and Chair of the Telecommunications Group. He is the Editor-in-Chief of Computer Networks (Elsevier) Journal since 2000 and the founding Editor-in-Chief of the Ad Hoc Networks Journal (2003) both published by Elsevier. Dr. Akyildiz is an IEEE FELLOW (1996) and an ACM FELLOW (1997). He received numerous awards from IEEE and ACM. Due to Google scholar, his papers received over 105+K citations and his h-index is 115 as of Ocrtober 2018. His current research interests are in Internet of xThings, 5G Wireless Systems, and Nano-Scale Communications.